Ira Mellman: from endosomes to industry

Ira Mellman: from endosomes to industry

Disease-related research requires a different kind of teamwork, says Ira Mellman. He hopes to find that team at his new home at Genentech.

Delivery of ligands from sorting endosomes to late endosomes occurs by maturation of sorting endosomes

After endocytosis, lysosomally targeted ligands pass through a series of endosomal compartments. The endocytic apparatus that accomplishes this passage may be considered to take one of two forms: (a) a system in which lysosomally targeted ligands pass through preexisting, long-lived early sorting endosomes and are then selectively transported to long-lived late endosomes in carrier vesicles, or...

IRA codes derived from Gruenbaum graph

. In this paper, we consider coding of short data frames (192 bits) by IRA codes. A new interleaver for the IRA codes based on a Gruenbaum graph is proposed. The difference of the proposed algorithm from known methods consists in the following: permutation is performed by using a match smaller interleaver which is derived from the Gruenbaum graph by finding in this graph a Hamiltonian path, enu...

Ira Gerhardt

SYMMETRIC INCLUSION - EXCLUSION Ira

One form of the inclusion-exclusion principle asserts that if A and B are functions of finite sets then the formulas A(S) = ∑ T⊆S B(T ) and B(S) = ∑ T⊆S(−1) |A(T ) are equivalent. If we replace B(S) by (−1)|S|B(S) then these formulas take on the symmetric form A(S) = ∑